Your Complete Guide to NCTF 135HA Injections: How They Transform Your Skin and Why It's a Must-Try

Are wrinkles, fine lines, and signs of ageing making you feel less confident in your skin? If you're nodding in agreement, you are not alone. The good news is that there's a solution worth exploring – NCTF 135HA injections. 

In this article, we'll take a comprehensive look at NCTF (New Cellular Treatment Factor) injections, a cutting-edge medical procedure designed to help you regain that youthful, radiant complexion you've been missing.

NCTF 135 HA injection
NCTF 135HA injections are effective for skin rejuvenation, texture improvement, and fine line and wrinkle reduction.

What is an NCTF 135HA injection? 

NCTF 135HA injection refers to a medical procedure where a product called NCTF (New Cellular Treatment Factor) is injected into the skin. NCTF 135HA is a complex solution composed of hyaluronic acid, vitamins, minerals, amino acids, and other essential nutrients. This mixture promotes skin rejuvenation, improves skin texture and appearance, and stimulates collagen production.

NCTF 135HA injections are often used in aesthetic and dermatological treatments to address issues such as wrinkles [1], fine lines, and skin hydration. The injected solution helps nourish the skin from within, promoting a more youthful and revitalised appearance.

Can NCTF 135HA address multiple skin issues effectively?

Due to their comprehensive formulation, NCTF 135HA injections can effectively address multiple skin issues. Here's how NCTF injections tackle various skin concerns:

  • Wrinkles and fine lines: NCTF 135HA contains hyaluronic acid [2], which can plump the skin and reduce the appearance of wrinkles and fine lines. Additionally, the vitamins and minerals in the solution promote skin health and support a smoother complexion.
  • Skin hydration: hyaluronic acid is a potent humectant [3], which means it attracts and retains moisture. NCTF 135HA injections help improve skin hydration by drawing in water molecules and preventing moisture loss, resulting in a more hydrated and radiant complexion.
  • Collagen production: the amino acids and essential nutrients in NCTF 135HA promote collagen synthesis [4]. Collagen is a structural protein responsible for the skin's firmness and elasticity. By stimulating collagen production, NCTF 135HA injections can help improve the skin's texture and overall appearance.
  • Skin rejuvenation: the combination of vitamins, minerals, and antioxidants in NCTF 135HA injection contributes to skin rejuvenation [5]. These ingredients nourish the skin, combat oxidative stress, and help repair damaged skin cells, leading to a more youthful and revitalised look.
Visible wrinkles and fine lines are signs of ageing.

In essence, NCTF 135HA injections provide a holistic approach to skin improvement. Targeting these key factors can effectively address various skin issues, leaving you with a refreshed, smoother, and more youthful complexion. 

How does the NCTF 135HA injection work? 

NCTF 135HA injections work by delivering a specially formulated complex of key components and ingredients directly into the skin. This complex is designed to rejuvenate the skin, improve its texture, and address various skin concerns. 

NCTF 135HA injections are administered by a medical professional, typically a dermatologist or aesthetic. The procedure involves using fine needles to introduce the NCTF solution directly into the skin, specifically in the dermal layer, which is deeper than superficial skin treatments.

What are the key components or ingredients of NCTF 135HA injections?

Here are the key components of the NCTF 135HA injections: 

  • Hyaluronic acid (HA): hyaluronic acid is a natural substance in the skin known for its excellent moisture-retaining properties. In NCTF 135HA injections, hyaluronic acid hydrates the skin, plumps it up, and reduces the appearance of fine lines and wrinkles.
  • Vitamins: NCTF 135HA contains various vitamins, such as vitamins A, B, C, and E. These vitamins have antioxidant properties that help protect the skin from free radical [6] damage, improve its overall health, and support collagen production.
  • Minerals: minerals like zinc, magnesium, and copper are essential for skin function and repair. They contribute to the overall health and vitality of the skin.
  • Amino acids: amino acids are the building blocks of proteins, including collagen. NCTF 135HA injections include amino acids [7] that encourage collagen production and help maintain skin elasticity and firmness.
  • Antioxidants: NCTF 135HA features antioxidants like glutathione [8], which combat oxidative stress and protect the skin from environmental damage. This can help in preventing premature ageing and improving skin quality.

Mechanism of action: the combination of these components works synergistically. Hyaluronic acid provides immediate hydration and plumping effects. Vitamins, minerals, and amino acids support the long-term health and vitality of the skin. 

The antioxidants protect the skin from damage caused by factors like UV radiation and pollution. Collectively, they stimulate collagen production, improve skin texture, reduce fine lines and wrinkles, and promote skin rejuvenation from within.

Is NCTF 135HA injection a type of mesotherapy?

Yes, NCTF 135HA injection is a type of mesotherapy [9]. Mesotherapy is a minimally invasive cosmetic procedure that involves injecting a combination of vitamins, minerals, amino acids, hyaluronic acid, and other active ingredients into the skin. Mesotherapy aims to rejuvenate the skin, promote collagen production, and address various skin concerns.

NCTF 135HA is a specific formulation used in mesotherapy procedures. It contains a blend of essential nutrients and hyaluronic acid, designed to improve skin texture, hydration, and overall quality. 

NCTF 135HA injections are typically administered in a series of sessions, and they work by nourishing the skin from within, promoting collagen synthesis, and enhancing the appearance and health of the skin.

Can NCTF 135HA injections truly banish stubborn dark eye circles?

NCTF 135 HA injections may help improve the appearance of dark eye circles [10], but their effectiveness in completely banishing them varies from person to person. The success of NCTF 135HA injections in addressing dark circles largely depends on the underlying causes of discolouration. 

Dark eye circles result from various factors, including genetics, thin under-eye skin, pigmentation issues, or vascular concerns. NCTF 135 HA injections primarily work by hydrating the skin, promoting collagen production, and rejuvenating the complexion, which can positively impact the appearance of the skin around the eyes.

However, for individuals with significant pigmentation or vascular issues contributing to their dark circles, additional treatments or strategies may be necessary to achieve the desired results. 

Is NCTF 135HA the solution to pigmentation problems and an even skin tone?

NCTF 135 HA injections can contribute to an overall improvement in skin texture, firmness, and elasticity through the stimulation of cell renewal and collagen production, and they may have a positive impact on reducing the appearance of pigmentation irregularities, fine lines, and wrinkles. 

However, it's important to note that NCTF 135 HA injections are not typically considered the primary or sole solution for pigmentation problems [11] and achieving an even skin tone. 

Specific pigmentation issues may require targeted treatments or skincare approaches to address these concerns effectively. NCTF 135HA injections may be used as part of a comprehensive skincare plan. Still, a tailored approach is often needed to directly address pigmentation problems and achieve a more uniform skin tone. 

Pigmentation issues, including dark spots and uneven skin tone, can be treated with NCTF 135HA injections.

Can NCTF 135HA injections help reduce wrinkles and fine lines?

Yes, NCTF 135HA injections can help reduce the appearance of wrinkles and fine lines. When injected into the skin, it works by:

  • Hydration: the hyaluronic acid in NCTF 135HA injections provides immediate hydration to the skin. Well-hydrated skin appears plumper and smoother, making fine lines and wrinkles less noticeable.
  • Collagen stimulation: NCTF 135HA injections stimulate collagen production in the skin. Collagen is a protein that provides structural support, and as we age, its production decreases, leading to the formation of wrinkles. By encouraging collagen synthesis, NCTF 135HA injection helps improve skin elasticity and reduce the depth of wrinkles.
  • Nourishment: the vitamins and minerals in NCTF 135HA injections nourish the skin, promoting overall skin health and supporting its ability to repair and regenerate, which can result in a more youthful appearance.

While NCTF injections can effectively reduce wrinkles and fine lines, the extent of the improvement varies from person to person. The results may also depend on the depth and type of wrinkles and the skin's overall condition.

Can NCTF 135HA injections minimise open pores for a flawless complexion?

NCTF 135 HA injections are primarily not intended for minimising open pores. These injections are formulated to address skin rejuvenation, hydration, and the reduction of concerns like fine lines and wrinkles and improvements in skin texture. 

While these injections can lead to a healthier and more radiant complexion, they do not specifically target the size of open pores. 

To minimise open pores and achieve a flawless complexion, other treatments and skincare strategies are typically more effective. Options like chemical peels, laser therapy, and specific skincare products containing pore-refining ingredients can help reduce the visibility of large pores.

Open pores
Enlarged or open pores result in uneven skin texture and imperfections.

What can I expect during an NCTF 135HA injection session?

During an NCTF 135HA injection session, you can generally expect the following steps:

  • Consultation: your session may begin with a consultation with a qualified aesthetic doctor. This is an opportunity to discuss your specific skin concerns, goals, and medical history to ensure that NCTF 135HA injections suit you.
  • Preparation: after the consultation, the treatment area, usually the face, is cleansed and prepared. Sometimes, topical anaesthetic cream or numbing agent [12] may be applied to minimise discomfort during the procedure.
  • Injection process: the NCTF 135HA solution directly into the skin via fine needles. The injections are typically administered in multiple areas on the face or other treatment areas as needed.
  • Monitoring: during the injections, your skin's response will be monitored to ensure the solution is evenly distributed and effectively reaching the target areas.
  • Post-procedure care: after the session, you may receive instructions for post-procedure care, which often includes recommendations for avoiding sun exposure, wearing sunscreen, and refraining from certain skincare products for a specified period.
  • Recovery: while minimal downtime is associated with NCTF 135HA injections, some individuals may experience mild redness, swelling, or bruising at the injection sites. These side effects are typically temporary and resolve within a few days.
  • Results: it may take a few weeks for the full effects of NCTF 135HA injections to become apparent. Over time, you can expect to see improvements in skin texture, hydration, and a reduction in fine lines and wrinkles.
NCTF 135 HA consultation
NCTF 135 HA injections are administered using fine needles.

Following the aftercare instructions and attending any recommended follow-up sessions is essential to achieve the best results. The specific details of the procedure may vary based on techniques and your individual needs, so be sure to discuss any questions or concerns with your aesthetic doctor during the consultation and throughout the process.

What are the side effects of NCTF 135HA injections?

NCTF 135 HA injections are generally considered safe, but like any medical procedure, they can be associated with some side effects. These side effects are typically mild and temporary. Common side effects of NCTF 135 HA injections may include:

  • Redness: mild redness at the injection sites is common and usually subsides within a few days.
  • Swelling: some individuals may experience minor swelling at the injection sites, which can last for a day or two.
  • Bruising: bruising may occur at the injection sites but is typically mild and can be concealed with makeup. It usually resolves within a few days to a week.
  • Tenderness: the treated areas may be tender to the touch for a short time after the procedure.
  • Itching: some people may experience mild itching at the injection sites, which is usually temporary.
  • Possibility of allergic reaction: while rare, there is a slight risk of an allergic reaction to one of the components in the NCTF solution. This can include redness, swelling, and itching. If you suspect an allergic reaction, contact the clinic promptly.
Itchy skin
Minor and temporary itching and redness are potential side effects of NCTF 125 HA injections.

It is important to note that these side effects are typically mild and resolve on their own within a short period. 

To minimise the risk of complications and ensure a safe and effective procedure, it is crucial to have NCTF 135 HA injections administered by a qualified aesthetician who can assess your suitability for the treatment and provide appropriate post-procedure care instructions.

How long are the effects of NCTF 135HA treatment?

The duration of NCTF 135 HA treatment results is not permanent and varies depending on individual factors. Typically, the effects are considered temporary, lasting from a few months to approximately a year. 

To maintain the benefits of NCTF treatment, many individuals opt for periodic maintenance sessions, the frequency of which is determined by their unique needs. Skincare practices, sun protection, and overall skin health influence the longevity of the results. Additionally, lifestyle factors like smoking and diet can impact the duration of results.

How often should I take NCTF 135HA treatment?

The frequency of NCTF 135 HA treatment sessions varies depending on your individual needs and treatment goals. However, a common recommendation is to undergo a series of 3 to 5 sessions, with approximately 2 to 3-week intervals between sessions. 

Your aesthetic doctor will assess your requirements and suggest a treatment schedule that best suits your skin concerns and objectives. After the initial series, maintenance sessions may be recommended at intervals to help sustain the results over time.

Who is an ideal candidate for NCTF 135HA injections?

NCTF 135 HA injections can be suitable for individuals looking to improve their skin's texture, hydration, and overall appearance. Ideal candidates often have the following characteristics:

  • Aged 30 and above: NCTF 135 HA injections are commonly used by individuals in their 30s and older, as this is the age range when signs of ageing and skin concerns like fine lines and wrinkles become more apparent.
  • Mild to moderate skin concerns: ideal candidates typically have mild to moderate skin concerns, including fine lines, wrinkles, dullness, and mild skin laxity. NCTF 135 HA is designed to address these issues effectively.
  • Good general health: candidates should have good overall health, without significant medical conditions that may contraindicate the procedure.
  • Seeking skin rejuvenation: those looking to rejuvenate their skin, improve hydration, and stimulate collagen production are often ideal candidates for NCTF 135HA injections.

Remember that NCTF 135HA injections are a versatile option, and the suitability of any candidate can be determined through a thorough consultation with your aesthetic doctor, who can assess individual needs and goals.

What are the contraindications and factors to consider before getting NCTF 135HA injections?

Before getting NCTF 135 HA injections, several contraindications and factors should be considered.


  • Allergies: if you have known allergies to any ingredients in NCTF 135HA, the treatment should be avoided to prevent allergic reactions.
  • Pregnancy and breastfeeding: NCTF 135HA injections are typically not recommended during pregnancy or while breastfeeding due to the lack of safety data in these circumstances.
  • Active skin infections: if you have an active skin infection, such as a cold sore or dermatitis, it is advisable to wait until the infection has cleared before undergoing NCTF treatment to prevent complications.
  • Autoimmune diseases: individuals with autoimmune diseases may not be suitable candidates for NCTF 135HA injections, as these conditions can affect the body's response to treatment.

Factors to consider:

  • Consultation: consulting a qualified aesthetic doctor is crucial to assessing your suitability for NCTF 135HA treatment. Your doctor will evaluate your specific skin concerns and overall health.
  • Realistic expectations: have realistic expectations about the outcomes of NCTF injections. While they can significantly improve your skin, they may not deliver the same results as more invasive procedures.
  • Medical history: discuss your medical history with your doctor, including any chronic medical conditions, medications, and previous cosmetic procedures.

Can people with acne or dark spots receive NCTF 135HA injections? 

NCTF 135HA injections are considered safe for individuals with acne or dark spots. However, it is important to note that NCTF injections are not a direct treatment for acne or dark spots. To address these concerns effectively, individuals with acne should follow appropriate skincare routines or consider medications and treatments specifically designed to manage acne. 

Dark spots, often caused by hyperpigmentation [13], may require targeted treatments such as topical creams, chemical peels, or laser therapies.

Finding the Perfect NCTF 135HA Injection Provider in Singapore: What to Consider

To ensure a safe and effective experience, you must consider the following aspects: 

  • Qualifications and credentials: verify that the aesthetic doctor is a licensed and qualified specialist with the appropriate training and credentials. 
  • Experience and expertise: look for an aesthetic doctor with a track record of administering NCTF 135HA injections and expertise in aesthetic and dermatological procedures.
  • Client reviews and testimonials: reading reviews and testimonials from previous clients can provide valuable insights into the doctor's reputation and the quality of their services.
  • Consultation process: a thorough consultation is essential. During this process, the doctor should discuss your treatment goals, assess your specific needs, and address any concerns you may have. It is an opportunity to establish a personalised treatment plan.
  • Safety and hygiene: prioritise safety and hygiene by ensuring that the clinic or doctor adheres to high standards of cleanliness and sterilisation. This is critical to prevent complications and infections.
  • Transparency and communication: choose an aesthetic doctor who communicates openly, explaining the procedure, potential side effects, and what you can expect before, during, and after the treatment.
  • Personalised treatment plans: opt for an aesthetic doctor who tailors the NCTF 135 HA injection treatment to your unique needs and goals. Everyone's skin is different, and a customised approach ensures the best possible results.

By considering these aspects and doing thorough research, you can increase the likelihood of finding a qualified and trustworthy NCTF 135HA injection provider who can help you achieve your desired skin care goals safely and effectively.

If you have any inquiries or reservations regarding NCTF 135HA injections and their suitability for your skincare needs, we encourage you to schedule a consultation with Dr. Lee Mun Heng

Dr. Lee is a seasoned expert in aesthetic medicine and can suggest the most appropriate treatment for your specific skin type and concerns.


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  3. Humectant: Examples and Benefits for Skin, Hair, and Lips. 31 Mar. 2022,
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  6. Lobo, V., et al. “Free Radicals, Antioxidants and Functional Foods: Impact on Human Health.” Pharmacognosy Reviews, vol. 4, no. 8, 2010, pp. 118–26. PubMed Central,
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  11. “Pigmentation Removal in Singapore - Dr Lee Mun Heng.” Dr Lee Mun Heng - Eyebag Removal | Skin Rejuvenation Singapore,   Accessed 19 Oct. 2023
  12. “What to Know About Skin-Numbing Cream.” Verywell Health,  Accessed 19 Oct. 2023. 
  13. “Hyperpigmentation: Age Spots, Sun Spots & Liver Spots.” Cleveland Clinic,  Accessed 19 Oct. 2023.

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